Journal article icon

Journal article

Atrial nitroso-redox balance and refractoriness following on-pump cardiac surgery: A randomised trial of atorvastatin

Abstract:

Aims

Systemic inflammation and increased activity of atrial NOX2-containing NADPH oxidases have been associated with the new onset of atrial fibrillation (AF) after cardiac surgery. In addition to lowering LDL-cholesterol, statins exert rapid anti-inflammatory and antioxidant effects, the clinical significance of which remains controversial.

Methods and results

We first assessed the impact of cardiac surgery and cardiopulmonary bypass...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Files:
Publisher copy:
10.1093/cvr/cvaa302

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
RDM Cardiovascular Medicine
Oxford college:
Lady Margaret Hall
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
RDM Cardiovascular Medicine
Role:
Author
ORCID:
0000-0003-3298-2697
Expand authors...
Publisher:
European Society of Cardiology Publisher's website
Journal:
Cardiovascular Research Journal website
Volume:
118
Issue:
1
Pages:
184-195
Place of publication:
England
Publication date:
2020-10-24
Acceptance date:
2020-10-12
DOI:
EISSN:
1755-3245
ISSN:
0008-6363
Pmid:
33098411
Language:
English
Keywords:
Pubs id:
1139830
Local pid:
pubs:1139830
Deposit date:
2020-11-30

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP