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Journal article

Economic evaluation of factorial randomised controlled trials: Challenges, methods and recommendations

Abstract:

Increasing numbers of economic evaluations are conducted alongside randomised controlled trials. Such studies include factorial trials, which randomise patients to different levels of two or more factors and can therefore evaluate the effect of multiple treatments alone and in combination. Factorial trials can provide increased statistical power or assess interactions between treatments, but raise additional challenges for trial-based economic evaluations: interactions may occur more commonly...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1002/sim.7322

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Nuffield Department of Population Health
Sub department:
Population Health
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Nuffield Department of Population Health
Sub department:
Population Health
Role:
Author
More from this funder
Funding agency for:
Gray, A
Grant:
NF-SI-0509-10206
Publisher:
Wiley
Journal:
Statistics in Medicine More from this journal
Volume:
36
Issue:
18
Pages:
2814-2830
Publication date:
2017-05-03
Acceptance date:
2017-04-04
DOI:
EISSN:
1097-0258
ISSN:
0277-6715
Language:
English
Keywords:
Pubs id:
pubs:687870
UUID:
uuid:19cd8e91-22b8-4310-b78e-00605ef83f3a
Local pid:
pubs:687870
Source identifiers:
687870
Deposit date:
2017-04-04

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