Journal article icon

Journal article

Genetically determined levels of circulating cytokines and risk of stroke: role of monocyte chemoattractant protein-1

Abstract:

Background: Cytokines and growth factors have been implicated in the initiation and propagation of vascular disease. Observational studies have shown associations of their circulating levels with stroke. Our objective was to explore whether genetically determined circulating levels of cytokines and growth factors are associated with stroke and its etiologic subtypes by conducting a 2-sample Mendelian randomization (MR) study.

Methods: Genetic instruments for 41 cytokines and growth ...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Authors


Georgakis, MK More by this author
Rannikmäe, K More by this author
Traylor, M More by this author
Anderson, CD More by this author
Expand authors...
Publisher:
American Heart Association Publisher's website
Journal:
Circulation Journal website
Volume:
139
Issue:
2
Pages:
256-268
Publication date:
2018-09-26
Acceptance date:
2018-08-17
DOI:
EISSN:
1524-4539
ISSN:
0009-7322
Pubs id:
pubs:955063
URN:
uri:19c6f854-70f8-4623-91a3-a4875ed72e06
UUID:
uuid:19c6f854-70f8-4623-91a3-a4875ed72e06
Local pid:
pubs:955063

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP