Journal article icon

Journal article

Heterogeneity and interplay of the extracellular vesicle small RNA transcriptome and proteome

Abstract:

Extracellular vesicles (EVs) mediate cell-to-cell communication by delivering or displaying macromolecules to their recipient cells. While certain broad-spectrum EV effects reflect their protein cargo composition, others have been attributed to individual EV-loaded molecules such as specific miRNAs. In this work, we have investigated the contents of vesicular cargo using small RNA sequencing of cells and EVs from HEK293T, RD4, C2C12, Neuro2a and C17.2. The majority of RNA content in EVs (49–9...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's Version

Actions


Access Document


Files:
Publisher copy:
10.1038/s41598-018-28485-9

Authors


More by this author
Role:
Author
ORCID:
0000-0002-5390-4420
More by this author
Role:
Author
ORCID:
0000-0003-4729-4205
Expand authors...
More from this funder
Funding agency for:
El Andaloussi, S
Expand funders...
Publisher:
Nature Publishing Group Publisher's website
Journal:
Scientific reports Journal website
Volume:
8
Chapter number:
10813
Publication date:
2018-07-17
Acceptance date:
2018-06-15
DOI:
EISSN:
2045-2322
Pubs id:
pubs:884850
URN:
uri:19132599-53f5-4298-990b-84e6c5ee7705
UUID:
uuid:19132599-53f5-4298-990b-84e6c5ee7705
Local pid:
pubs:884850
Language:
English
Keywords:

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP