Journal article
Heterogeneity and interplay of the extracellular vesicle small RNA transcriptome and proteome
- Abstract:
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Extracellular vesicles (EVs) mediate cell-to-cell communication by delivering or displaying macromolecules to their recipient cells. While certain broad-spectrum EV effects reflect their protein cargo composition, others have been attributed to individual EV-loaded molecules such as specific miRNAs. In this work, we have investigated the contents of vesicular cargo using small RNA sequencing of cells and EVs from HEK293T, RD4, C2C12, Neuro2a and C17.2. The majority of RNA content in EVs (49–9...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
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(Version of record, pdf, 2.4MB)
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- Publisher copy:
- 10.1038/s41598-018-28485-9
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Authors
Funding
+ Biotechnology and Biological Sciences Research Council
More from this funder
Funding agency for:
Wood, M
+ Swedish Foundation for Strategic Research
More from this funder
Funding agency for:
El Andaloussi, S
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Bibliographic Details
- Publisher:
- Nature Publishing Group Publisher's website
- Journal:
- Scientific reports Journal website
- Volume:
- 8
- Publication date:
- 2018-07-17
- Acceptance date:
- 2018-06-15
- DOI:
- EISSN:
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2045-2322
- Pmid:
-
30018314
- Source identifiers:
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884850
Item Description
- Language:
- English
- Keywords:
- Pubs id:
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pubs:884850
- UUID:
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uuid:19132599-53f5-4298-990b-84e6c5ee7705
- Local pid:
- pubs:884850
- Deposit date:
- 2018-07-31
Terms of use
- Copyright holder:
- Sork et al
- Copyright date:
- 2018
- Notes:
-
© The Author(s) 2018. Open Access This article is licensed under a Creative Commons Attribution 4.0 International
License, which permits use, sharing, adaptation, distribution and reproduction in any medium or
format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative
Commons license, and indicate if changes were made.
- Licence:
- CC Attribution (CC BY)
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