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The ILT family of leukocyte receptors.

Abstract:

In this short review we examine the recently identified immunoglobulin-like transcript (ILT) family of receptors (also known as LIR and MIR). ILT are expressed by many leukocyte subsets, especially monocytic cells. Expression levels of certain ILT molecules allow definition of blood monocyte and dendritic cell (DC) subsets. Two receptors, ILT2 and ILT4, recognise a broad range of MHC class I molecules and transduce an inhibitory signal. Such recognition may give many cell lineages the potenti...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
NDM Experimental Medicine
Role:
Author
Journal:
Immunobiology
Volume:
202
Issue:
1
Pages:
34-41
Publication date:
2000-05-01
DOI:
EISSN:
1878-3279
ISSN:
0171-2985
Source identifiers:
31713
Language:
English
Keywords:
Pubs id:
pubs:31713
UUID:
uuid:188eaf1f-3499-48f3-8ce2-d3ccc271dc70
Local pid:
pubs:31713
Deposit date:
2012-12-19

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