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The ILT family of leukocyte receptors.

Abstract:

In this short review we examine the recently identified immunoglobulin-like transcript (ILT) family of receptors (also known as LIR and MIR). ILT are expressed by many leukocyte subsets, especially monocytic cells. Expression levels of certain ILT molecules allow definition of blood monocyte and dendritic cell (DC) subsets. Two receptors, ILT2 and ILT4, recognise a broad range of MHC class I molecules and transduce an inhibitory signal. Such recognition may give many cell lineages the potenti...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Experimental Medicine Division,
Role:
Author
Journal:
Immunobiology
Volume:
202
Issue:
1
Pages:
34-41
Publication date:
2000-05-05
DOI:
EISSN:
1878-3279
ISSN:
0171-2985
URN:
uuid:188eaf1f-3499-48f3-8ce2-d3ccc271dc70
Source identifiers:
31713
Local pid:
pubs:31713

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