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Living network meta-analysis compared with pairwise meta-analysis in comparative effectiveness research: empirical study.

Abstract:

Objectives

To examine whether the continuous updating of networks of prospectively planned randomised controlled trials (RCTs) (‘living’ network meta-analysis) provides strong evidence against the null hypothesis in comparative effectiveness of medical interventions earlier than the updating of conventional, pairwise meta-analysis.

Design

Empirical study of the accumulating evidence about the comparative effectiveness of clinical interventions.

Data Sour...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1136/bmj.k585

Authors


Nikolakopoulou, A More by this author
Mavridis, D More by this author
Furukawa, TA More by this author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Psychiatry
ORCID:
0000-0001-5179-8321
Tricco, AC More by this author
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Canada Research Chair More from this funder
National Instute of Health Research More from this funder
Publisher:
BMJ Publishing Group Publisher's website
Journal:
BMJ Journal website
Volume:
360
Pages:
k585
Publication date:
2018-02-05
Acceptance date:
2018-01-22
DOI:
EISSN:
1756-1833
ISSN:
0959-8138
Pubs id:
pubs:828565
URN:
uri:1867b711-860f-4e7e-9e70-36f457f24e54
UUID:
uuid:1867b711-860f-4e7e-9e70-36f457f24e54
Local pid:
pubs:828565

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