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Statin treatment for children and adolescents with heterozygous familial hypercholesterolaemia: a systematic review and meta-analysis.

Abstract:

AIMS: To assess efficacy and safety of HMG-CoA reductase inhibitor (statin) treatment in children and adolescents with heterozygous familial hypercholesterolaemia. METHODS: MEDLINE, EMBASE, COCHRANE and Current Controlled Trials databases were searched. Study design, efficacy, and safety outcome-measures were extracted. Results of parallel-group randomised placebo controlled trials with low density (LDL) and high density lipoprotein cholesterol (HDL), and triglycerides as outcomes were pooled...

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Publication status:
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Authors


Arambepola, C More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Primary Care Health Sciences, Biomedical RC
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Primary Care Health Sciences, Biomedical RC
More by this author
Institution:
University of Oxford
Department:
Oxford
Journal:
Atherosclerosis
Volume:
195
Issue:
2
Pages:
339-347
Publication date:
2007-12-05
DOI:
EISSN:
1879-1484
ISSN:
0021-9150
URN:
uuid:17dad180-1c54-440e-84f0-49ea14044aed
Source identifiers:
33668
Local pid:
pubs:33668

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