A multicentre randomized controlled trial of epidural corticosteroid injections for sciatica: the WEST study.

Journal article

OBJECTIVE: To determine the effectiveness and predictors of response to lumbar epidural corticosteroid injections (ESI) in patients with sciatica. We performed a 12-month, multicentre, double-blind, randomized, placebo-controlled, parallel-group trial in four secondary pain-care clinics in the Wessex Region. METHODS: Two hundred and twenty-eight patients with a clinical diagnosis of unilateral sciatica of 1-18 months' duration were randomized to either three lumbar ESIs of triamcinolone acet...

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Authors: Arden, N; Price, C; Reading, I; Stubbing, J; Hazelgrove, J

• Publication status: Published
• Journal: Rheumatology (Oxford, England)
• Volume: 44
• Issue: 11
• Pages: 1399-1406
• Publication date: 2005-11-01
• DOI: 10.1093/rheumatology/kei028
• EISSN: 1462-0332
• ISSN: 1462-0324
• Language: English
• Keywords: Adolescent; Anti-Inflammatory Agents; Male; Follow-Up Studies; Aged; Injections, Epidural; Adult; WEST Study Group; Sciatica; Middle Aged; Pain Measurement; Treatment Outcome; Disability Evaluation; Glucocorticoids; Double-Blind Method; Female; Humans; Triamcinolone Acetonide