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Thesis

Evaluation of immune correlates to TB vaccines

Abstract:

Development of an improved TB vaccine is hindered by the lack of a correlate of protection. Efficacy of TB vaccines in humans can only be assessed by expensive and time consuming trials within TB endemic areas, which are limited; therefore, it is critical that vaccines with the greatest potential to protect are selected for these trials. Mycobacterial growth inhibition assays (MGIAs) have been developed with the hope that these in vitro functional assays will correlate with protec...

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Institution:
University of Oxford
Research group:
Jenner Institute
Oxford college:
Wolfson College
Department:
Medical Sciences Division - Clinical Medicine,Nuffield Department of
Role:
Author

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Role:
Supervisor
Publication date:
2011
Type of award:
DPhil
Level of award:
Doctoral
Language:
English
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