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Journal article

Cognate MHC-TCR interaction leads to apoptosis of antigen-presenting cells.

Abstract:

Antigen presentation to T lymphocytes has been characterized extensively in terms of T lymphocyte activation and eventual cell death. In contrast, little is known about the consequences of antigen presentation for the antigen-presenting cell (APC). We have determined the outcome of major histocompatibility complex class II-restricted peptide presentation to a specific T cell. We demonstrate that specific T lymphocyte interaction with peptide-presenting APCs led to apoptosis in the APC populat...

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Publication status:
Published

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Publisher copy:
10.1189/jlb.0703356

Authors


Setterblad, N More by this author
Blancheteau, V More by this author
Delaguillaumie, A More by this author
Bécart, S More by this author
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Journal:
Journal of leukocyte biology
Volume:
75
Issue:
6
Pages:
1036-1044
Publication date:
2004-06-05
DOI:
EISSN:
1938-3673
ISSN:
0741-5400
URN:
uuid:1768e5dd-76aa-4f70-93bf-c6824a2def3a
Source identifiers:
30969
Local pid:
pubs:30969

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