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Global antibiotic dosing strategies in hospitalised children: characterising variation and implications for harmonisation of international guidelines

Abstract:

Background
Paediatric global antibiotic guidelines are inconsistent, most likely due to the limited pharmacokinetic and efficacy data in this population. We investigated factors underlying variation in antibiotic dosing using data from five global point prevalence surveys.
Methods & findings
Data from 3,367 doses of the 16 most frequent intravenous antibiotics administered to children 1 month–12 years across 23 countries were analysed. For ea... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1371/journal.pone.0252223

Authors


Publisher:
Public Library of Science
Journal:
PLoS One More from this journal
Volume:
16
Issue:
5
Article number:
e0252223
Publication date:
2021-05-27
Acceptance date:
2021-05-11
DOI:
ISSN:
1932-6203
Language:
English
Keywords:
Pubs id:
1179385
Local pid:
pubs:1179385
Deposit date:
2021-05-29

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