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Apnea-hypopnea index, nocturnal arousals, oxygen desaturation and structural brain changes: A population-based study

Abstract:

Sleep apnea has been related to brain changes such as atrophy. However, which component of sleep apnea, the apnea-hypopnea index (AHI), nocturnal oxygen desaturation or arousals, can explain this association is unclear. In this large population-based study (n=681, mean age 62.1 years), we investigated the associations of AHI, nocturnal oxygen desaturation and arousals with global and regional gray matter and white matter volumes and with white matter lesion volumes. All participants underwent...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1016/j.nbscr.2016.04.001

Authors


Zuurbier, LA More by this author
Vernooij, MW More by this author
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Department:
Oxford, MSD, Clinical Neurosciences
Kocevska, D More by this author
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Publisher:
Elsevier Publisher's website
Journal:
Neurobiology of Sleep and Circadian Rhythms Journal website
Volume:
1
Issue:
1
Pages:
1-7
Publication date:
2016-10-05
DOI:
ISSN:
2451-9944
Pubs id:
pubs:647896
URN:
uri:172d4e97-c678-4a53-9b29-bdf4cfe40bd4
UUID:
uuid:172d4e97-c678-4a53-9b29-bdf4cfe40bd4
Local pid:
pubs:647896
Paper number:
1

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