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Journal article

Phase-dependent suppression of beta oscillations in Parkinson’s disease patients

Abstract:

Synchronized oscillations within and between brain areas facilitate normal processing, but are often amplified in disease. A prominent example is the abnormally sustained beta-frequency (~20Hz) oscillations recorded from the cortex and subthalamic nucleus of Parkinson’s disease patients. Computational modelling suggests that the amplitude of such oscillations could be modulated by applying stimulation at a specific phase. Such a strategy would allow selective targeting of the oscillation, wit...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's Version

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Publisher copy:
10.1523/JNEUROSCI.1913-18.2018

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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Pharmacology
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Pharmacology
Oxford college:
Brasenose College
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Pharmacology
Role:
Author
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More from this funder
Funding agency for:
Kormann, E
Publisher:
Society for Neuroscience Publisher's website
Journal:
Journal of Neuroscience Journal website
Volume:
39
Issue:
6
Pages:
1119-1134
Publication date:
2018-12-14
Acceptance date:
2018-11-20
DOI:
EISSN:
1529-2401
ISSN:
0270-6474
Pubs id:
pubs:946899
URN:
uri:169f970d-b4ac-4eb7-b5aa-392f3134c491
UUID:
uuid:169f970d-b4ac-4eb7-b5aa-392f3134c491
Local pid:
pubs:946899

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