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The tachykinin NK3 receptor antagonist SR142801 blocks the behavioral effects of cocaine in marmoset monkeys.

Abstract:

Brain neuropeptide transmitters of the tachykinin family are involved in the organization of many behaviors. However, little is known about their contribution to the behavioral effects of drugs of abuse. Recently, the tachykinin NK3 receptor, one of the three tachykinin receptors in the brain, was shown to attenuate the acute and chronic behavioral effects of cocaine in rats. In order to test if these findings can be generalized to primates we investigated the role of the tachykinin NK3 recep...

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience
Role:
Author
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Journal:
European journal of pharmacology
Volume:
536
Issue:
3
Pages:
269-278
Publication date:
2006-05-05
DOI:
EISSN:
1879-0712
ISSN:
0014-2999
URN:
uuid:16894f76-5b88-40d3-844b-963c673ff268
Source identifiers:
240880
Local pid:
pubs:240880

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