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Thesis

Investigating circuits underlying acetylcholine-evoked striatal dopamine release in health and disease

Abstract:

Dopamine (DA) is a key striatal neuromodulator central to normal functioning of the basal ganglia. Identifying and characterizing circuits governing striatal DA transmission is necessary for understanding DA involvement in adaptive behaviour and pathology. Properties of evoked striatal DA release can be examined using fast-scan cyclic voltammetry at carbon fibre microelectrodes, a technique enabling live monitoring of transmitter release events with sub-millisecond resolution. Experimenta...

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Institution:
University of Oxford
Research group:
Cragg
Oxford college:
Christ Church
Department:
Medical Sciences Division - Physiology,Anatomy and Genetics,Department of
Role:
Author

Contributors

Role:
Supervisor
Role:
Supervisor
Publication date:
2014
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
Oxford University, UK
URN:
uuid:1675813e-0b07-4ede-9094-cdc442679394
Local pid:
ora:9345

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