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Collar occupancy: A new quantitative imaging tool for morphometric analysis of oligodendrocytes

Abstract:

Background Oligodendrocytes (OL) are the myelinating cells of the central nervous system. OL differentiation from oligodendrocyte progenitor cells (OPC) is accompanied by characteristic stereotypical morphological changes. Quantitative imaging of those morphological alterations during OPC differentiation is commonly used for characterization of new molecules in cell differentiation and myelination and screening of new pro-myelinating drugs. Current available imaging analysis methods imply a n...

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Publication status:
Published
Peer review status:
Peer reviewed

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Institution:
University of Oxford
Division:
Medical Sciences Division
Role:
Author
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Funding agency for:
Cruz, A
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Funding agency for:
Mendes Pinto, I
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Publisher:
Elsevier Publisher's website
Journal:
Journal of Neuroscience Methods Journal website
Volume:
294
Pages:
122-135
Publication date:
2017-11-22
Acceptance date:
2017-11-19
DOI:
EISSN:
1872-678X
ISSN:
0165-0270
Pubs id:
pubs:810746
URN:
uri:16599480-0dfa-4d8e-99c4-8738096ed408
UUID:
uuid:16599480-0dfa-4d8e-99c4-8738096ed408
Local pid:
pubs:810746

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