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Addressing the gender-knowledge gap in glucose-6-phosphate dehydrogenase deficiency: challenges and opportunities

Abstract:

G6PD deficiency is a common X-linked genetic trait, with an associated enzyme deficiency phenotype, whereby males are either G6PD deficient or normal, but females exhibit a broader range of G6PD-deficiency, ranging from severe deficiency to normal. Heterozygous females typically have intermediate G6PD enzyme activity levels. In the malaria field, G6PD deficiency has significant implications for the safe and appropriate treatment for P.vivax malaria, as individuals with this deficiency are at ...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's Version

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Publisher copy:
10.1093/inthealth/ihy060

Authors


Domingo, GJ More by this author
Satyagraha, AW More by this author
Sibley, CH More by this author
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Funding agency for:
Parker, MJ
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Funding agency for:
Kelley, M
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Publisher:
Oxford University Press Publisher's website
Journal:
International Health Journal website
Publication date:
2018-09-03
Acceptance date:
2018-07-20
DOI:
EISSN:
1876-3405
Pubs id:
pubs:894290
URN:
uri:1547d695-b95e-4b6d-9c52-8271c8f0c639
UUID:
uuid:1547d695-b95e-4b6d-9c52-8271c8f0c639
Local pid:
pubs:894290

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