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Global and regional dissemination and evolution of Burkholderia pseudomallei.

Abstract:

The environmental bacterium Burkholderia pseudomallei causes an estimated 165,000 cases of human melioidosis per year worldwide, and is also classified as a biothreat agent. We used whole genome sequences of 469 B. pseudomallei isolates from 30 countries collected over 79 years to explore its geographic transmission. Our data point to Australia as an early reservoir, with transmission to Southeast Asia followed by onward transmission to South Asia, and East Asia. Repeated reintroduction was o...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted manuscript

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Publisher copy:
10.1038/nmicrobiol.2016.263

Authors


Chewapreecha, C More by this author
Holden, MT More by this author
Vehkala, M More by this author
Välimäki, N More by this author
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Funding agency for:
Limmathurotsakul, D
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Funding agency for:
Dance, D
COIN Centre of Excellence More from this funder
Helsinki Institute of Information Technology More from this funder
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Publisher:
Nature Publishing Group Publisher's website
Journal:
Nature Microbiology Journal website
Volume:
2
Pages:
16263
Publication date:
2017-01-05
Acceptance date:
2016-08-12
DOI:
EISSN:
2058-5276
Pubs id:
pubs:673212
URN:
uri:152614f8-0d19-4b07-979d-8717e52621a2
UUID:
uuid:152614f8-0d19-4b07-979d-8717e52621a2
Local pid:
pubs:673212
Language:
English
Keywords:

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