Journal article
Genetic variants linked to education predict longevity
- Abstract:
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Educational attainment is associated with many health outcomes, including longevity. It is also known to be substantially heritable. Here, we used data from three large genetic epidemiology cohort studies (Generation Scotland, n = ∼17,000; UK Biobank, n = ∼115,000; and the Estonian Biobank, n = ∼6,000) to test whether education-linked genetic variants can predict lifespan length. We did so by using cohort members’ polygenic profile score for education to predict their parents’ longevity. Acro...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
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(Preview, Accepted manuscript, pdf, 384.1KB, Terms of use)
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- Publisher copy:
- 10.1073/pnas.1605334113
Authors
Funding
Bibliographic Details
- Publisher:
- National Academy of Sciences
- Journal:
- Proceedings of the National Academy of Sciences More from this journal
- Volume:
- 113
- Issue:
- 47
- Pages:
- 13366–13371
- Publication date:
- 2016-01-01
- Acceptance date:
- 2016-09-20
- DOI:
- EISSN:
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1091-6490
- ISSN:
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0027-8424
Item Description
- Keywords:
- Pubs id:
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pubs:661145
- UUID:
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uuid:14cd32f6-1133-409c-9ba3-21e7467a6d5b
- Local pid:
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pubs:661145
- Source identifiers:
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661145
- Deposit date:
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2016-11-22
Terms of use
- Copyright holder:
- Marioni et al
- Copyright date:
- 2016
- Notes:
- This is the accepted manuscript version of the article. The final version is available online from National Academy of Sciences at: https://doi.org/10.1073/pnas.1605334113
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