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Blood Pressure and Risk of Vascular Dementia: Evidence From a Primary Care Registry and a Cohort Study of Transient Ischemic Attack and Stroke.

Abstract:

Vascular dementia is the second most common form of dementia but reliable evidence on age-specific associations between blood pressure (BP) and risk of vascular dementia is limited and some studies have reported negative associations at older ages.In a cohort of 4.28 million individuals, free of known vascular disease and dementia and identified from linked electronic primary care health records in the United Kingdom (Clinical Practice Research Datalink), we related BP to time to physician-di...

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Publication status:
Published

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Publisher copy:
10.1161/STROKEAHA.116.012658

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Department:
St Edmund Hall
Role:
Author
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Department:
Oxford, MSD, Obstetrics & Gynaecology
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Author
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Contributors

Department:
From the George Institute for Global Health (C.A.E., G.S.-K., A.K., N.C., T.C., S.G.A., H.M., M.W., K.R.), Stroke Prevention Research Unit, Nuffield Department of Clinical Neurosciences (P.M.R., Z.M., S.T.P.), and Division of Cardiovascular Medicine, Radcliffe Department of Medicine (K.R.), University of Oxford, United Kingdom; The George Institute for Global Health, University of Sydney, Australia (M.W.); and Department of Epidemiology, Johns Hopkins University, Baltimore, MD (M.W.).
OSRP2/1006/The Dunhill Medical Trust More from this funder
095626/Wellcome Trust More from this funder
Publisher:
American Heart Association
Journal:
Stroke; a journal of cerebral circulation
Issue:
6
Publication date:
2016-06-05
Acceptance date:
2016-04-13
DOI:
ISSN:
1524-4628 and 0039-2499
Pubs id:
pubs:616197
URN:
uri:14b5c716-c391-44c4-a24a-44722e2077c3
UUID:
uuid:14b5c716-c391-44c4-a24a-44722e2077c3
Local pid:
pubs:616197

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