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Dose-intensified hypofractionated stereotactic body radiation therapy for painful spinal metastases: Results of a phase 2 study

Abstract:

The objective of this study was to prospectively evaluate dose-intensified hypofractionated stereotactic body radiation therapy (SBRT) in patients with painful spinal metastases in a multicenter, single-arm, phase 2 study.Patients with 2 or fewer distinct, noncontiguous, painful, mechanically stable, unirradiated spinal metastases from a solid tumor with a Karnofsky performance status ≥ 60 were eligible. Patients with a long (Mizumoto score ≤ 4) or intermediate overall survival expectancy (Mi...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1002/cncr.31294

Authors


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Role:
Author
ORCID:
0000-0002-7146-9071
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Institution:
University of Oxford
Division:
MSD
Department:
Oncology
Sub department:
CRUK/MRC Ox Inst for Radiation Oncology
Role:
Author
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Grant:
Biomedical Research Centre for ICR/RMH
Publisher:
Wiley Publisher's website
Journal:
Cancer Journal website
Volume:
124
Issue:
9
Pages:
2001-2009
Publication date:
2018-03-02
Acceptance date:
2018-01-05
DOI:
EISSN:
1097-0142
ISSN:
0008-543X
Pmid:
29499073
Source identifiers:
828839
Language:
English
Keywords:
Pubs id:
pubs:828839
UUID:
uuid:14a7c5d8-1d6d-44ce-8ae2-0f6953354043
Local pid:
pubs:828839
Deposit date:
2018-03-15

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