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Thesis

Approaches to developing novel bioengineered skin substitutes

Abstract:

In this body of work, a new method of creating a tunable porous scaffold - emulsion templating - to reconstitute the dermal layer of skin was explored. This method has traditionally been used to create polymeric high internal phase emulsions (polyHIPEs). The challenge of using emulsions for templating protein hydrogel networks is the preservation of native protein conformation in an emulsion system.

In this instance, a non-ionic surfactant blend was used to create a metastable bio...

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Role:
Supervisor
Role:
Supervisor
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Funding agency for:
Xuxin Lim
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford

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