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Anamnestic immune response and safety of an inactivated quadrivalent influenza vaccine in primed versus vaccine-naïve children

Abstract:
Background: It has not yet been demonstrated whether two doses of inactivated quadrivalent influenza vaccine (IIV4) prime a booster response in infants. We evaluated the anamnestic immune response to an IIV4 in children aged 17−48 months. Methods: Children were randomized to two doses of IIV4 or control in the primary phase III study (NCT01439360). One year later, in an open-label revaccination extension study (NCT01702454), a subset of children who received... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1097/INF.0000000000002217

Authors


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GlaxoSmithKline Biologicals SA More from this funder
Publisher:
Wolters Kluwer Publisher's website
Journal:
Pediatric Infectious Disease Journal Journal website
Volume:
38
Issue:
2
Pages:
203-210
Publication date:
2018-10-15
Acceptance date:
2018-09-18
DOI:
EISSN:
1532-0987
ISSN:
0891-3668
Pmid:
30325891
Source identifiers:
929663
Language:
English
Keywords:
Pubs id:
pubs:929663
UUID:
uuid:13efbf09-8e31-411b-84ed-cd560d725177
Local pid:
pubs:929663
Deposit date:
2018-10-20

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