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Cargo release from polymeric vesicles under shear

Abstract:

In this paper we study the release of cargo from polymeric nano-carriers under shear. Vesicles formed by two star block polymers-A12B6C2(ABC) and A12B6A2(ABA)-and one linear block copolymer-A14B6(AB), are investigated using dissipative particle dynamics (DPD) simulations. A- and C-blocks are solvophobic and B-block is solvophilic. The three polymers form vesicles of different structures. The vesicles are subjected to shear both in bulk and between solvophobic walls. In bulk shear, the mechani...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's Version

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Publisher copy:
10.3390/polym10030336

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Institution:
University of Oxford
Division:
MPLS Division
Department:
Engineering Science
Oxford college:
St Johns College
Role:
Author
Publisher:
MDPI Publisher's website
Journal:
Polymers Journal website
Volume:
10
Issue:
3
Pages:
336
Publication date:
2018-03-19
Acceptance date:
2018-03-16
DOI:
EISSN:
2073-4360
Pubs id:
pubs:832464
URN:
uri:13d85dd6-c5c0-46bf-bc6e-2135bc423896
UUID:
uuid:13d85dd6-c5c0-46bf-bc6e-2135bc423896
Local pid:
pubs:832464

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