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A reassessment of genetic diversity in Icelanders: strong evidence from multiple loci for relative homogeneity caused by genetic drift.

Abstract:

There has been some controversy in the literature concerning whether Icelanders are genetically homogenous or heterogeneous relative to other European populations. We reassess this question in the light of large data sets spanning 83 autosomal SNP loci, 14 serogenetic loci, 6622 Y-chromosomes and 3214 sequences from mtDNA hypervariable segments 1 and 2 (HVS1 and HVS2). Our results strongly support the hypothesis that genetic drift, with a consequent loss of variation, has had a greater impact...

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Publication status:
Published

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Authors


Helgason, A More by this author
Nicholson, G More by this author
Stefánsson, K More by this author
Donnelly, P More by this author
Journal:
Annals of human genetics
Volume:
67
Issue:
Pt 4
Pages:
281-297
Publication date:
2003-07-05
DOI:
EISSN:
1469-1809
ISSN:
0003-4800
URN:
uuid:13c0b394-beb6-4240-ba74-0ad0e5b6e3e2
Source identifiers:
50024
Local pid:
pubs:50024

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