Journal article
Molecular cross-talk between the transcription, translation, and nonsense-mediated decay machineries.
- Abstract:
-
It is widely believed that translation occurs only in the cytoplasm of eukaryotes, but recent results suggest some takes place in nuclei, coupled to transcription. Support for this heterodoxy comes from studies of the nonsense-mediated decay (NMD) pathway; this pathway probably uses ribosomes to proofread messenger RNAs. We find components of the machineries involved in transcription, translation and NMD colocalise, interact and copurify, and that interactions between them are probably mediat...
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- Publication status:
- Published
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Bibliographic Details
- Journal:
- Journal of cell science
- Volume:
- 117
- Issue:
- Pt 6
- Pages:
- 899-906
- Publication date:
- 2004-02-01
- DOI:
- EISSN:
-
1477-9137
- ISSN:
-
0021-9533
- Source identifiers:
-
12646
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:12646
- UUID:
-
uuid:139c6436-5d70-4649-9131-4017f70444b9
- Local pid:
- pubs:12646
- Deposit date:
- 2012-12-19
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- Copyright date:
- 2004
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