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HIV-specific cytotoxic T-cells in HIV-exposed but uninfected Gambian women

Abstract:

A crucial requirement in the rational design of a prophylactic vaccine against the human immunodeficiency virus (HIV) is to establish whether or not protective immunity can occur following natural infection. The immune response to HIV infection is characterized by very vigorous HIV-specific cytotoxic T-lymphocyte (CTL) activity. We have identified four HIV-1 and HIV- 2 cross-reactive peptide epitopes, presented to CTL from HIV-infected Gambians by HLA-B35 (the most common Gambian class I HLA ...

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Authors


Rowland-Jones, S More by this author
Ariyoshi, K More by this author
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Journal:
Nature Medicine
Volume:
1
Issue:
1
Pages:
59-64
Publication date:
1995
ISSN:
1078-8956
URN:
uuid:13635509-13a8-4235-86cb-5f7849793a20
Source identifiers:
176687
Local pid:
pubs:176687
Language:
English

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