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HER2 significance and treatment outcomes after radiotherapy for brain metastases in breast cancer patients.

Abstract:

The aim of this retrospective study was to examine the influence of HER2 status on outcome in breast cancer patients following whole brain radiotherapy (WBRT) for cerebral metastases. One hundred and eighty one patients with recordable HER2 status, who received WBRT at single institution were identified and stratified according to HER2 status. Eighty eight were HER2 positive (HER2+) (49%) and 93 HER2 negative (HER2-) (51%). A total of 72 (82%) HER2+ group developed brain metastases whilst on ...

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Institution:
University of Oxford
Department:
Oxford, MSD, Oncology
Role:
Author
Journal:
Breast
Volume:
17
Issue:
6
Pages:
661-665
Publication date:
2008-12-05
DOI:
EISSN:
1532-3080
ISSN:
0960-9776
URN:
uuid:133c5d57-7870-47f2-85f1-bc662107aeaa
Source identifiers:
366074
Local pid:
pubs:366074

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