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An evolving story of the metastatic voyage of ovarian cancer cells: Cellular and molecular orchestration of the adipose-rich metastatic microenvironment

Abstract:

Metastasis is a complex multistep process that involves critical interactions between cancer cells and a variety of stromal components in the tumor microenvironment, which profoundly influence the different aspects of the metastatic cascade and organ tropism of disseminating cancer cells. Ovarian cancer is the most lethal gynecological malignancy and is characterized by peritoneal disseminated metastasis. Evidence has demonstrated that ovarian cancer possesses specific metastatic tropism fo...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1038/s41388-018-0637-x

Authors


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Institution:
University of Oxford
Department:
RDM
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Women’s & Reproductive Health
Role:
Author
More by this author
Institution:
University of Oxford
Department:
RDM
Role:
Author
More by this author
Institution:
University of Oxford
Department:
RDM
Role:
Author
More by this author
Institution:
University of Oxford
Department:
RDM
Role:
Author
More from this funder
Name:
Wellbeing of Women Scholarship
Funding agency for:
Wietek, N
More from this funder
Name:
National Institute for Health Research
Grant:
Oxford Biomedical Research Centre
Publisher:
Springer Nature
Journal:
Oncogene More from this journal
Volume:
38
Pages:
2885–2898
Publication date:
2018-12-19
Acceptance date:
2018-11-19
DOI:
ISSN:
1476-5594
Keywords:
Pubs id:
pubs:945684
UUID:
uuid:132f9aae-7c42-4b01-805f-b468fdf0177d
Local pid:
pubs:945684
Source identifiers:
945684
Deposit date:
2018-11-22

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