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Journal article

KILchip v1.0: a novel plasmodium falciparum merozoite protein microarray to facilitate malaria vaccine candidate prioritization

Abstract:

Passive transfer studies in humans clearly demonstrated the protective role of IgG antibodies against malaria. Identifying the precise parasite antigens that mediate immunity is essential for vaccine design, but has proved difficult. Completion of the Plasmodium falciparum genome revealed thousands of potential vaccine candidates, but a significant bottleneck remains in their validation and prioritization for further evaluation in clinical trials. Focusing initially on the Plasmodium falcipar...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's Version

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Publisher copy:
10.3389/fimmu.2018.02866

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Publisher:
Frontiers Media Publisher's website
Journal:
Frontiers in Immunology Journal website
Volume:
9
Pages:
2866
Publication date:
2018-12-11
Acceptance date:
2018-11-21
DOI:
EISSN:
1664-3224
Pubs id:
pubs:955450
URN:
uri:1312794f-d80d-453d-b776-febdc563da52
UUID:
uuid:1312794f-d80d-453d-b776-febdc563da52
Local pid:
pubs:955450

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