Journal article
KILchip v1.0: a novel plasmodium falciparum merozoite protein microarray to facilitate malaria vaccine candidate prioritization
- Abstract:
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Passive transfer studies in humans clearly demonstrated the protective role of IgG antibodies against malaria. Identifying the precise parasite antigens that mediate immunity is essential for vaccine design, but has proved difficult. Completion of the Plasmodium falciparum genome revealed thousands of potential vaccine candidates, but a significant bottleneck remains in their validation and prioritization for further evaluation in clinical trials. Focusing initially on the Plasmodium falcipar...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's Version
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- Files:
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(pdf, 6.1MB)
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- Publisher copy:
- 10.3389/fimmu.2018.02866
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Authors
Funding
Bibliographic Details
- Publisher:
- Frontiers Media Publisher's website
- Journal:
- Frontiers in Immunology Journal website
- Volume:
- 9
- Pages:
- 2866
- Publication date:
- 2018-12-11
- Acceptance date:
- 2018-11-21
- DOI:
- EISSN:
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1664-3224
- Pubs id:
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pubs:955450
- URN:
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uri:1312794f-d80d-453d-b776-febdc563da52
- UUID:
-
uuid:1312794f-d80d-453d-b776-febdc563da52
- Local pid:
- pubs:955450
Item Description
Terms of use
- Copyright holder:
- Kamuyu et al.
- Copyright date:
- 2018
- Notes:
- © 2018 Kamuyu, Tuju, Kimathi, Mwai, Mburu, Kibinge, Chong Kwan, Hawkings, Yaa, Chepsat, Njunge, Chege, Guleid, Rosenkranz, Kariuki, Frank, Kinyanjui, Murungi, Bejon, Färnert, Tetteh, Beeson, Conway, Marsh, Rayner and Osier. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
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