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Risk of adverse events following the initiation of antihypertensives in older people with complex health needs: a self-controlled case series in the United Kingdom

Abstract:

Background: We assessed the risk of adverse events—severe acute kidney injury (AKI), falls and fractures—associated with use of antihypertensives in older patients with complex health needs (CHN).

Setting: UK primary care linked to inpatient and mortality records.

Methods: The source population comprised patients aged >65, with ≥1 year of registration and unexposed to antihypertensives in the year before study start. We ide...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1093/ageing/afad177

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Sub department:
Botnar Research Centre
Role:
Author
ORCID:
0000-0002-0000-0110
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Sub department:
Botnar Research Centre
Role:
Author
ORCID:
0000-0003-4470-2736
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Sub department:
Botnar Research Centre
Role:
Author
ORCID:
0000-0003-0388-3403
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Sub department:
Botnar Research Centre
Role:
Author
ORCID:
0000-0002-3950-6346
Publisher:
Oxford University Press
Journal:
Age and Ageing More from this journal
Volume:
52
Issue:
9
Article number:
afad177
Place of publication:
England
Publication date:
2023-09-16
DOI:
EISSN:
1468-2834
ISSN:
0002-0729
Pmid:
37725973
Language:
English
Keywords:
Pubs id:
1536914
Local pid:
pubs:1536914
Deposit date:
2023-10-16

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