Journal article icon

Journal article

Crystallization and preliminary X-ray analysis of mouse RANK and its complex with RANKL.

Abstract:

The interaction between the TNF-family molecule receptor activator of NF-kappaB ligand (RANKL) and its receptor RANK induces osteoclast formation, activation and survival in the process of bone remodelling. RANKL-RANK also plays critical roles in T-cell/dendritic cell communication and lymph-node formation and in a variety of pathologic conditions such as tumour-cell migration and bone metastasis. Both the ectodomain of mouse RANKL and the extracellular domain of mouse RANK have been cloned, ...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1107/s1744309109015735

Authors


Expand authors...
Journal:
Acta crystallographica. Section F, Structural biology and crystallization communications
Volume:
65
Issue:
Pt 6
Pages:
597-600
Publication date:
2009-06-01
DOI:
EISSN:
1744-3091
ISSN:
1744-3091
Source identifiers:
14086

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP