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Effect of point-of-care C-reactive protein testing on antibiotic prescription in febrile patients attending primary care in Thailand and Myanmar: an open-label, randomised, controlled trial

Abstract:
Background In southeast Asia, antibiotic prescription in febrile patients attending primary care is common, and a probable contributor to the high burden of antimicrobial resistance. The objective of this trial was to explore whether C-reactive protein (CRP) testing at point of care could rationalise antibiotic prescription in primary care, comparing two proposed thresholds to classify CRP concentrations as low or high to guide antibiotic treatment. Methods ... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1016/s2214-109x(18)30444-3

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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDM
Oxford college:
Lady Margaret Hall
ORCID:
0000-0002-6997-3877
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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDM
Subgroup:
Tropical Medicine
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Grant:
Institutional Strategic Support Fundgrant (105605/Z/14/Z)
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Grant:
Foundation for Innovative New Diagnostics
Publisher:
Elsevier Publisher's website
Journal:
Lancet Global Health Journal website
Volume:
7
Issue:
1
Pages:
e119-e131
Publication date:
2018-12-13
Acceptance date:
2018-09-15
DOI:
ISSN:
2214-109X
Pubs id:
pubs:954413
URN:
uri:12c4f44b-78c8-4c01-a2bf-1bc22117ec47
UUID:
uuid:12c4f44b-78c8-4c01-a2bf-1bc22117ec47
Local pid:
pubs:954413
Language:
English

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