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Journal article

Site-selective traceless Staudinger ligation for glycoprotein synthesis reveals scope and limitations.

Abstract:
Making it traceless: A traceless Staudinger reaction between a specifically functionalized sugar phosphine and an azide-tagged protein allows the construction of well-defined reverse N-linked glycoproteins (see scheme). This reaction was applied to different azidoprotein substrates and its potentials and limitations are outlined. © 2011 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim.
Publication status:
Published

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Publisher copy:
10.1002/cbic.201100125

Authors


Bernardes, GJ More by this author
Linderoth, L More by this author
Doores, KJ More by this author
Boutureira, O More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MPLS, Chemistry, Organic Chemistry
Journal:
Chembiochem : a European journal of chemical biology
Volume:
12
Issue:
9
Pages:
1383-1386
Publication date:
2011-06-05
DOI:
EISSN:
1439-7633
ISSN:
1439-4227
URN:
uuid:12c3d847-cc96-44c3-b226-b5f477142cfb
Source identifiers:
141692
Local pid:
pubs:141692

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