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What brain signals are suitable for feedback control of deep brain stimulation in Parkinson's disease?

Abstract:

Feedback control of deep brain stimulation (DBS) in Parkinson's disease has great potential to improve efficacy, reduce side effects, and decrease the cost of treatment. In this, the timing and intensity of stimulation are titrated according to biomarkers that capture current clinical state. Stimulation may be at standard high frequency or intelligently patterned to directly modify specific pathological rhythms. The search for and validation of appropriate feedback signals are therefore cruci...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience, Biomedical Research Centre
Role:
Author
Journal:
Annals of the New York Academy of Sciences
Volume:
1265
Issue:
1
Pages:
9-24
Publication date:
2012-08-05
DOI:
EISSN:
1749-6632
ISSN:
0077-8923
URN:
uuid:12c2649f-6aa9-4320-a40e-6e319b691eff
Source identifiers:
344205
Local pid:
pubs:344205

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