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Increased cerebral functional connectivity in ALS: a resting-state magnetoencephalography study

Abstract:
Objective We sought to assess cortical function in amyotrophic lateral sclerosis (ALS) using noninvasive neural signal recording. Methods Resting-state magnetoencephalography was used to measure power fluctuations in neuronal oscillations from distributed cortical parcels in 24 patients with ALS and 24 healthy controls. A further 9 patients with primary lateral sclerosis and a group of 15 asymptomatic carriers of genetic mutations associated with ALS were al... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1212/WNL.0000000000005333

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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Oxford Centre for Human Brain Activity
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Oxford Centre for Human Brain Activity
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Oxford Centre for Human Brain Activity
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Clinical Neurosciences
Role:
Author
Publisher:
American Academy of Neurology
Journal:
Neurology More from this journal
Volume:
90
Issue:
16
Pages:
e1418-e1424
Publication date:
2018-03-21
Acceptance date:
2018-01-11
DOI:
EISSN:
0028-3878
ISSN:
1526-632X
Keywords:
Pubs id:
pubs:817694
UUID:
uuid:12abb848-0396-486f-a579-2a8554386b8a
Local pid:
pubs:817694
Source identifiers:
817694
Deposit date:
2018-01-11

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