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Post-treatment haemolysis in African children with hyperparasitaemic falciparum malaria; a randomized comparison of artesunate and quinine

Abstract:
Background Parenteral artesunate is the treatment of choice for severe malaria. Recently, haemolytic anaemia occurring 1 to 3 weeks after artesunate treatment of falciparum malaria has been reported in returning travellers in temperate countries. Methods To assess these potential safety concerns in African children, in whom most deaths from malaria occur, an open-labelled, randomized controlled trial was conducted in Kinshasa, Democratic Republic of Congo. 2... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1186/s12879-017-2678-0

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Tropical Medicine
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Tropical Medicine
Role:
Author
Guilin Pharmaceutical More from this funder
Publisher:
BioMed Central Publisher's website
Journal:
BMC Infectious Diseases Journal website
Volume:
17
Issue:
1
Article number:
575
Publication date:
2017-08-17
Acceptance date:
2017-08-09
DOI:
ISSN:
1471-2334
Pmid:
28818049
Language:
English
Pubs id:
pubs:724104
UUID:
uuid:1293d668-89c7-4710-b64b-abb05235c100
Local pid:
pubs:724104
Source identifiers:
724104
Deposit date:
2017-09-07

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