Journal article
Population pharmacokinetics and pharmacodynamics of lumefantrine in young Ugandan children treated with artemether-lumefantrine for uncomplicated malaria
- Abstract:
-
The pharmacokinetics and pharmacodynamics of lumefantrine, a component of the most widely used treatment for malaria, artemether-lumefantrine, has not been adequately characterized in young children.Capillary whole-blood lumefantrine concentration and treatment outcomes were determined in 105 Ugandan children, ages 6 months to 2 years, who were treated for 249 episodes of Plasmodium falciparum malaria with artemether-lumefantrine.Population pharmacokinetics for lumefantrine used a 2-compartme...
Expand abstract
- Publication status:
- Published
- Peer review status:
- Peer reviewed
Actions
Authors
Funding
+ Doris Duke Charitable
Foundation
More from this funder
Grant:
clinical scientist development award to S. P. [grant
2007055
+ President′s Emergency Plan for
AIDS Relief
More from this funder
Grant:
throughtheDepartmentofHealth
HumanServices/Centers
forDiseaseControl
Prevention(U62P024421
National Center
for HIV, Viral Hepatitis, STD, and TB Prevention
More from this funder
Expand funders...
Bibliographic Details
- Publisher:
- Oxford University Press Publisher's website
- Journal:
- Journal of Infectious Diseases Journal website
- Volume:
- 214
- Issue:
- 8
- Pages:
- 1243-1251
- Publication date:
- 2016-10-01
- Acceptance date:
- 2016-07-23
- DOI:
- EISSN:
-
1537-6613
- ISSN:
-
0022-1899
- Pmid:
-
27471317
- Source identifiers:
-
638619
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:638619
- UUID:
-
uuid:12775a58-bb47-48dc-a7cf-7fd9f1d522f4
- Local pid:
- pubs:638619
- Deposit date:
- 2016-10-11
Terms of use
- Copyright holder:
- Tchaparian et al
- Copyright date:
- 2016
- Notes:
-
Copyright © The Author 2016. Published by Oxford University Press for the Infectious Diseases Society of America.
This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited.
If you are the owner of this record, you can report an update to it here: Report update to this record