Journal article
Catalytic activity of catalase-silica nanoparticle hybrids: from ensemble to individual entity activity
- Abstract:
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We demonstrate the electrochemical detection and characterization of individual nanoparticle-enzyme hybrids. Silica nanoparticles were functionalized with catalase enzyme and investigated spectroscopically and electrochemically. The catalytic activity of the hybrids towards hydrogen peroxide decomposition was comparable to the activity of a freely diffusing enzyme in solution, exhibiting a Michaelis-Menten constant of KM = 74 mM and a turnover number of kcat = 8 × 10(7) s(-1) per NP. The fast...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, pdf, 632.0KB)
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- Publisher copy:
- 10.1039/c6sc04921d
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Authors
Funding
+ European Research Council
More from this funder
Funding agency for:
Sepunaru, L
Grant:
FP/2007–2013/ERC320403
+ European Research Council
More from this funder
Funding agency for:
Sokolov, S
Grant:
FP/2007–2013/ERC320403
+ European Research Council
More from this funder
Funding agency for:
Kätelhön, E
Grant:
FP/2007–2013/ERC320403
Bibliographic Details
- Publisher:
- Royal Society of Chemistry Publisher's website
- Journal:
- Chemical Science Journal website
- Volume:
- 8
- Issue:
- 3
- Pages:
- 2303-2308
- Publication date:
- 2016-12-15
- Acceptance date:
- 2016-12-14
- DOI:
- EISSN:
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2041-6539
- ISSN:
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2041-6520
- Source identifiers:
-
685406
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:685406
- UUID:
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uuid:12558877-037e-496b-b159-2754818f230f
- Local pid:
- pubs:685406
- Deposit date:
- 2017-06-07
Terms of use
- Copyright holder:
- Chan et al
- Copyright date:
- 2016
- Notes:
- This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
- Licence:
- CC Attribution (CC BY)
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