Journal article
Bone Morphogenetic Protein and Notch signaling crosstalk in poor-prognosis, mesenchymal-subtype colorectal cancer
- Abstract:
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The functional role of Bone Morphogenetic Protein (BMP) signaling in colorectal cancer (CRC) is poorly defined, with contradictory results in cancer cell line models reflecting the inherent difficulties of assessing a signaling pathway that is context dependent and subject to genetic constraints. By assessing the transcriptional response of a diploid human colonic epithelial cell line to BMP ligand stimulation we generated a prognostic BMP signaling signature, which was applied to multiple...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, pdf, 4.8MB)
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- Publisher copy:
- 10.1002/path.4891
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Authors
Funding
Bibliographic Details
- Publisher:
- Wiley Publisher's website
- Journal:
- Journal of Pathology Journal website
- Volume:
- 242
- Issue:
- 2
- Pages:
- 178-192
- Publication date:
- 2017-05-03
- Acceptance date:
- 2017-02-21
- DOI:
- EISSN:
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1096-9896
- ISSN:
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0022-3417
- Source identifiers:
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681334
Item Description
- Keywords:
- Pubs id:
-
pubs:681334
- UUID:
-
uuid:12375377-16ef-45d7-bc64-64768fae76d8
- Local pid:
- pubs:681334
- Deposit date:
- 2017-02-21
Terms of use
- Copyright holder:
- © 2017 Irshad, et al
- Copyright date:
- 2017
- Notes:
- This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
- Licence:
- CC Attribution (CC BY)
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