Cytogenetic and epigenetic analysis of human gametes and preimplantation embryos

Thesis

Despite major advances in the assisted reproductive treatments, it remains the case that most embryos transferred to the uterus fail to implant or are lost shortly after. Chromosome aneuploidy has been characterised as one of the major factors impacting embryo viability.

While the incidence of whole chromosome aneuploidies has been well characterised, little is known about segmental aneuploidy affecting fragments of chromosomes. One of the aims of this study was to investigate the ...

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Authors: Babariya, D

• Type of award: DPhil
• Level of award: Doctoral
• Awarding institution: University of Oxford