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Mechanistic roles of protein disorder within transcription

Abstract:

Understanding the interactions of proteins involved in transcriptional regulation is critical to describing biological systems because they control the expression profile of the cell. Yet sadly they belong to a less well biophysically characterized subset of proteins; they frequently contain long disordered regions that are highly dynamic. A key question therefore is, why? What functional roles does protein disorder play in transcriptional regulation? Experimental data exemplifying these...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.sbi.2017.02.003

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Biochemistry
Role:
Author
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Funding agency for:
Shammas, S
Grant:
MR/N024168/1
Publisher:
Elsevier Publisher's website
Journal:
Current Opinion in Structural Biology Journal website
Volume:
42
Pages:
155–161
Publication date:
2017-01-01
Acceptance date:
2017-02-17
DOI:
ISSN:
0959-440X
Source identifiers:
681400
Pubs id:
pubs:681400
UUID:
uuid:11b6ab82-84ee-45df-ae25-f15730ff6f5d
Local pid:
pubs:681400
Deposit date:
2017-02-22

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