Improving sensitivity and specificity in diffusion MRI group studies

Thesis

Diffusion MRI provides a unique opportunity to study the brain tissue architecture at a microscopic level. More specifically, it allows to infer biophysical properties of the axons in the white matter in-vivo. Microstructural parameters are widely used in multi-subject studies to track pathological processes, follow normal development and aging, or investigate behaviour. This thesis aims to identify and potentially address the limitations and pitfalls in voxelwise comparison of diffusion M...

Expand abstract

Authors: Vallee, E

• Type of award: DPhil
• Level of award: Doctoral
• Awarding institution: University of Oxford
• Language: English
• Keywords: diffusion mri; computational neurology; group studies; machine learning
• Subjects: diffusion mri; group studies; white matter biomarkers