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Thesis

Investigation of the dose and temporal effects of intravenous iron on human cardiopulmonary physiology

Abstract:

Sustained hypoxia induces a progressive rise in pulmonary artery systolic pressure (PASP). Intravenous (IV) iron administered immediately prior to the hypoxic exposure attenuates this effect, suggesting that manipulation of iron stores may modify hypoxia-induced pulmonary hypertension. Not yet understood is the duration of effect of IV iron, or the dose-response relationship between clinical indices of iron status and modest loading of iron in non-iron deficient individuals. To address thi...

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Division:
MSD
Department:
Physiology Anatomy & Genetics
Department:
University of Oxford
Role:
Author

Contributors

Department:
University of Oxford
Role:
Supervisor
Department:
University of Oxford
Role:
Supervisor
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
UUID:
uuid:11a0a3be-8db1-459a-a3f9-0aae25ff0d13
Deposit date:
2018-07-23

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