Journal article
Selective release of muscle-specific, extracellular microRNAs during myogenic differentiation.
- Abstract:
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MyomiRs are muscle-specific microRNAs (miRNAs) that regulate myoblast proliferation and differentiation. Extracellular myomiRs (ex-myomiRs) are highly enriched in the serum of Duchenne Muscular Dystrophy (DMD) patients and dystrophic mouse models and consequently have potential as disease biomarkers. The biological significance of miRNAs present in the extracellular space is not currently well understood. Here we demonstrate that ex-myomiR levels are elevated in perinatal muscle development, ...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, pdf, 890.8KB)
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(Version of record, pdf, 1.0MB)
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- Publisher copy:
- 10.1093/hmg/ddw237
Authors
Funding
Bibliographic Details
- Publisher:
- Oxford University Press Publisher's website
- Journal:
- Human Molecular Genetics Journal website
- Volume:
- 25
- Issue:
- 18
- Pages:
- 3960-3974
- Publication date:
- 2016-07-27
- Acceptance date:
- 2016-07-11
- DOI:
- EISSN:
-
1460-2083
- ISSN:
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0964-6906
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:636434
- UUID:
-
uuid:118d28ee-9517-4634-8df0-90d1e0c024eb
- Local pid:
- pubs:636434
- Source identifiers:
-
636434
- Deposit date:
- 2016-08-22
Terms of use
- Copyright holder:
- Coenen-Stass et al
- Copyright date:
- 2016
- Notes:
- © The Author 2016. Published by Oxford University Press. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License.
- Licence:
- CC Attribution (CC BY)
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