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Serum undercarboxylated osteocalcin correlates with hemoglobin A1c in children with recently diagnosed pediatric diabetes

Abstract:

Background

Osteocalcin (OC), a hormone secreted by osteoblasts, improves beta-cell function in vitro and in vivo. We aimed to understand the relationship between OC and hemoglobin A1c (HbA1c) in pediatric diabetes.

Methods

Children (n = 70; mean [SD] age = 11.8 years [3.1]; 34.3% non-Hispanic white, 46.3% Hispanic, 14.9% African-American, 4.5% other) newly diagnosed with diabetes (69.1% type 1 diabetes [T1D], 30.9% type 2 diabetes [T2D]) were studied. We collected...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1111/pedi.12501

Authors


Redondo, MJ More by this author
More by this author
Department:
Oxford, MSD, NDORMS
Texas Children’s Pilot Award More from this funder
Vivian L. Smith Foundation More from this funder
Methodist Physician organization More from this funder
Publisher:
Wiley Publisher's website
Journal:
Pediatric Diabetes Journal website
Publication date:
2017-01-05
Acceptance date:
2016-12-16
DOI:
ISSN:
1399-543X
Pubs id:
pubs:688046
URN:
uri:10f99eb5-5a73-48d6-afa9-f913700a1528
UUID:
uuid:10f99eb5-5a73-48d6-afa9-f913700a1528
Local pid:
pubs:688046

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