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Glibenclamide and metfoRmin versus stAndard care in gEstational diabeteS (GRACES): a feasibility open label randomised trial

Abstract:
Background: Metformin is widely used to treat gestational diabetes (GDM), but many women remain hyperglycaemic and require additional therapy. We aimed to determine recruitment rate and participant throughput in a randomised trial of glibenclamide compared with standard therapy insulin (added to maximum tolerated metformin) for treatment of GDM. Methods: We conducted an open label feasibility study in 5 UK antenatal clinics among pregnant women 16 to 36 weeks... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1186/s12884-017-1505-3

Authors


Reynolds, RM More by this author
Denison, FC More by this author
More by this author
Department:
Oxford, MSD, Nuffield Dept of Population Health, NPEU
More by this author
Department:
Oxford, MSD, Nuffield Dept of Population Health, NPEU
Penneycard, J More by this author
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Publisher:
BioMed Central Publisher's website
Journal:
BMC Pregnancy and Childbirth Journal website
Volume:
17
Issue:
1
Pages:
Article: 316
Publication date:
2017-09-22
Acceptance date:
2017-09-10
DOI:
ISSN:
1471-2393
Pubs id:
pubs:726240
URN:
uri:10714b98-aed4-4c97-bb90-05c6a74b397d
UUID:
uuid:10714b98-aed4-4c97-bb90-05c6a74b397d
Local pid:
pubs:726240

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