Journal article icon

Journal article

Dynamic combinatorial chemistry employing boronic acids/boronate esters leads to potent oxygenase inhibitors.

Abstract:
Dynamic duo: The reversible reaction of boronic acids with alcohols to form boronate esters, coupled to protein mass spectrometry analyses, was used to discover potent oxygenase inhibitors. This dynamic combinatorial mass spectrometry technique could potentially be applied to the identification of other protein inhibitors. Copyright © 2012 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim.
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1002/anie.201202000

Authors


Expand authors...
Journal:
Angewandte Chemie (International ed. in English)
Volume:
51
Issue:
27
Pages:
6672-6675
Publication date:
2012-07-05
DOI:
EISSN:
1521-3773
ISSN:
1433-7851
URN:
uuid:0ee6d569-7dd4-4287-a20f-464492ac351d
Source identifiers:
334704
Local pid:
pubs:334704

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP