Journal article
Diagnostic value of cerebrospinal fluid alpha-synuclein seed quantification in synucleinopathies
- Abstract:
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Several studies have confirmed α-synuclein real-time quaking-induced conversion (αSyn-RT-QuIC) assay to have high sensitivity and specificity for Parkinson’s disease. However, whether the assay can be used as a robust, quantitative measure to monitor disease progression, stratify different synucleinopathies and predict disease conversion in patients with idiopathic REM sleep behaviour disorder remains undetermined. The aim of this study was to assess the diagnostic value of CSF aSyn-RT-QuIC q...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Preview, Version of record, 770.6KB, Terms of use)
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- Publisher copy:
- 10.1093/brain/awab431
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Funding
Bibliographic Details
- Publisher:
- Oxford University Press
- Journal:
- Brain More from this journal
- Volume:
- 145
- Issue:
- 2
- Pages:
- 584–595
- Publication date:
- 2021-12-11
- Acceptance date:
- 2021-11-01
- DOI:
- EISSN:
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1460-2156
- ISSN:
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0006-8950
- Pmid:
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34894214
Item Description
- Language:
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English
- Keywords:
- Pubs id:
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1224494
- Local pid:
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pubs:1224494
- Deposit date:
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2022-01-28
Terms of use
- Copyright holder:
- Poggiolini et al.
- Copyright date:
- 2021
- Rights statement:
- ©2021 The Author(s). Published by Oxford University Press on behalf of the Guarantors of Brain. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
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