Thesis icon

Thesis

A biophysical study of the G protein coupled receptor neurotensin receptor 1

Abstract:

Neurotensin (NT) is a tridecapeptide neurotransmitter found in the central nervous system and gastrointestinal tract. Neurotensin receptor 1 (NTS1), a high affinity receptor for NT, is a member of the GPCR superfamily and is a putative target for the treatment of conditions such as Schizophrenia, Parkinson’s Disease and drug addiction.

Overexpression and purification are typically limiting steps in the high resolution structure determination of GPCRs. In this study, through the op...

Expand abstract

Actions


Authors


More by this author
Institution:
University of Oxford
Research group:
Prof. Anthony Watts
Oxford college:
Queen's College, The
Department:
Medical Sciences Division - Biochemistry

Contributors

Role:
Supervisor
Publication date:
2007
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
Oxford University, UK
URN:
uuid:0e84f351-696f-42c9-b2fd-8afcde6d586e
Local pid:
ora:10118

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP