Thesis
A biophysical study of the G protein coupled receptor neurotensin receptor 1
- Abstract:
-
Neurotensin (NT) is a tridecapeptide neurotransmitter found in the central nervous system and gastrointestinal tract. Neurotensin receptor 1 (NTS1), a high affinity receptor for NT, is a member of the GPCR superfamily and is a putative target for the treatment of conditions such as Schizophrenia, Parkinson’s Disease and drug addiction.
Overexpression and purification are typically limiting steps in the high resolution structure determination of GPCRs. In this study, through the op...
Expand abstract
Actions
+ Medical Research Council
More from this funder
- Funder identifier:
- http://dx.doi.org/10.13039/501100000265
- Funding agency for:
- Harding, PJ
+ Biotechnology and Biological Sciences Research Council
More from this funder
- Funding agency for:
- Harding, PJ
- Publication date:
- 2007
- DOI:
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
- Language:
-
English
- Keywords:
- Subjects:
- UUID:
-
uuid:0e84f351-696f-42c9-b2fd-8afcde6d586e
- Local pid:
-
ora:10118
- Deposit date:
-
2015-02-18
Terms of use
- Copyright holder:
- Harding, P
- Copyright date:
- 2007
- Notes:
- This thesis is not currently available in ORA
If you are the owner of this record, you can report an update to it here: Report update to this record